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NSR-RPGR abstracts presented at EURETINA 2018 Congress approved affidavit of abstraction with abiding dose-related improvements apparent as aboriginal as ages 1 above assorted microperimetry analyses

Preliminary adeptness signals empiric in 3/3 patients in accomplice 3 and 2/6 patients in cohorts 4 and 5, including abiding improvements in all-embracing birthmark sensitivity, axial 16 birthmark acuteness and cardinal of bigger birthmark loci

NSR-RPGR was well-tolerated with no dosage attached toxicities or austere treatment-related adverse events

XIRIUS amplification abstraction planned to admit in Q4 2018

Detailed after-effects to be presented at R&D day on September 24, 2018

WALTHAM, Mass. and LONDON, Sept. 22, 2018 (GLOBE NEWSWIRE) — Nightstar Therapeutics plc (NASDAQ:NITE), a clinical-stage gene assay aggregation developing treatments for attenuate affiliated retinal diseases, today appear that absolute basic assurance and adeptness abstracts of NSR-RPGR from the dosage accretion abstraction in the Phase 1/2 XIRIUS balloon were presented today at the EURETINA 2018 Congress.

“We accomplished this abstraction aftermost year, with the apprehension of demonstrating assurance and stabilization of ache with NSR-RPGR, our codon-optimized gene assay for XLRP,” said Tuyen Ong, M.D., arch development administrator of Nightstar. “Based on the

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